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dimethylchloromethylphosphine oxide

CHLOROMETHYLDIMETHYLPHOSPHINE OXIDE

CAS: 1638-75-1

Molecular Formula: C3H8ClOP

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dimethylchloromethylphosphine oxide - Names and Identifiers

Name CHLOROMETHYLDIMETHYLPHOSPHINE OXIDE
Synonyms CHLOROMETHYLDIMETHYLPHOSPHINE OXIDE
dimethylchloromethylphosphine oxide
[chloromethyl(methyl)phosphoryl]methane
Phosphine oxide, (chloromethyl)dimethyl-
CAS 1638-75-1
EINECS 216-675-1

dimethylchloromethylphosphine oxide - Physico-chemical Properties

Molecular FormulaC3H8ClOP
Molar Mass126.52
Density1.113±0.06 g/cm3(Predicted)
Melting Point70.5-71 °C
Boling Point80-83 °C(Press: 1 Torr)

dimethylchloromethylphosphine oxide - Introduction

CHLOROMETHYLDIMETHYLPHOSPHINE OXIDE is an organophosphorus compound with the chemical formula (CH3)2 POCH2Cl. The following is an introduction to the nature, use, formulation and safety information of CHLOROMETHYLDIMETHYLPHOSPHINE OXIDE:

Nature:
- CHLOROMETHYLDIMETHYLPHOSPHINE OXIDE is a colorless or pale yellow liquid with a pungent odor.
-It is soluble in organic solvents such as ethanol, ethers and chlorinated hydrocarbons, but insoluble in water.
-It is an organic electrophilic reagent with strong electrophilicity and is easy to react with nucleophiles.

Use:
- CHLOROMETHYLDIMETHYLPHOSPHINE OXIDE can be used for oxidation and phosphating reactions in organic synthesis.
-It is commonly used as a reagent for the establishment of phosphorus heterocycles, nucleophilic substitution reactions of alcohol ethers, and phosphine oxide propanol rearrangement reactions of esters.

Preparation Method:
- CHLOROMETHYLDIMETHYLPHOSPHINE OXIDE can be prepared by the reaction of methyl chloromethyl phosphine chloride and trimethylamine.

Safety Information:
- CHLOROMETHYLDIMETHYLPHOSPHINE OXIDE is irritating and corrosive, be careful to wear personal protective equipment such as gloves, goggles and lab coats when handling.
-Flammability, avoid contact with open flame and oxygen.
-Storage should avoid high temperature and direct sunlight. It is recommended to store in a cool and ventilated place, and avoid mixing with other organic substances and oxidants.
-in the use and disposal process should be strictly in accordance with the relevant safety operation specifications for operation, to prevent harm to the human body and the environment.
Last Update:2024-04-10 22:29:15
dimethylchloromethylphosphine oxide
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